FIG. 3.

Healthy lung morphology is preserved after treatment with enoxaparin (ENOX) post-TBI. (A–D) H&E staining of lung sections from naïve (A) TBI-UN, (B) TBI-vehicle–treated (C), and enoxaparin-treated (D) mice 30 min after TBI and collected 24 h post-TBI. Enoxaparin-treated mice showed less evidence of acute lung injury. (E) Acute lung injury scoring was significantly decreased in enoxaparin versus TBI-vehicle mice. Data presented as mean ± SEM. N = 5–6 per group; **p < 0.01; *p < 0.05 compared to sham. ALI, acute lung injury; H&E, hematoxylin-eosin; SEM, standard error of the mean; TBI, traumatic brain injury; TBI-UN, TBI-untreated.