FIG. 4.
Kinetics of pmeLUC. (A) Representative kinetic curve of pmeLUC bioluminescent activity after intraperitoneal injection (i.p.) of 150 mg/kg of D-Luciferin. Peak signal is reached ∼10 min after i.p. injection. Representative kinetic curve of sham animal (B), CCI animal (C), and CCI treated with APT102 (D). Dotted lines and gray area indicate time elapsed during sham and CCI surgery. CCI, controlled cortical impact.