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. Author manuscript; available in PMC: 2021 Feb 22.
Published in final edited form as: N Engl J Med. 2019 Mar 21;380(12):1150–1157. doi: 10.1056/NEJMoa1807841

Figure 1. Laboratory Data after Onset of Fragility Fractures.

Figure 1.

Shown are clinical laboratory results for alkaline phosphatase, parathyroid hormone, serum calcium, and phosphate after the onset of fragility fractures. To convert the values for calcium to millimoles per liter, multiply by 0.250. To convert the values for phosphate to millimoles per liter, multiply by 0.3229. Shaded areas show reference ranges: alkaline phosphatase, 30 to 115 U per liter and 30 to 145 U per liter; parathyroid hormone, 13 to 54 pg per milliliter and 7 to 37 pg per milliliter; calcium, 8.4 to 10.2 mg per deciliter; and phosphate, 2.5 to 4.6 mg per deciliter. The change in reference ranges for alkaline phosphatase and parathyroid hormone are the result of changes in instrumentation in the clinical laboratory during the time the measurements were obtained. Gray bars at the top of the figure provide a chronologic timeline of vitamin D supplementation. IM denotes intramuscular, and UVB ultraviolet B.

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