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. 2021 Feb 22;17:21. doi: 10.1186/s13223-021-00516-7

Table 4.

Association of sleep problems with asthma, allergic rhinitis, eczema

Sleep problems, odds ratio (95% confidence interval)
Subscale 1 p p* Subscale 2 p p* Subscale 3 p p* Subscale 4 p p* Subscale 5 p p* Subscale 6 p p*
Asthma
 Adjusted model 1 0.98 (0.75–1.27) 0.85 0.98 1.26 (0.95–1.67) 0.11 0.27 1.16 (0.89–1.51) 0.28 0.52 1.01 (0.69–1.46) 0.98 0.98 1.90 (1.34–2.69) < 0.001 < 0.001 1.12 (0.83–1.52) 0.46 0.77
 Adjusted model 2 1.01 (0.77–1.32) 0.96 0.96 1.28 (0.96–1.70) 0.09 0.23 1.17 (0.90–1.53) 0.25 0.47 0.99 (0.68–1.44) 0.95 0.96 1.87 (1.32–2.66) < 0.001 < 0.001 1.11 (0.82–1.51) 0.51 0.77
 Adjusted model 3 1.00 (0.77–1.31) 0.98 1.00 1.25 (0.94–1.67) 0.12 0.30 1.14 (0.87–1.50) 0.34 0.63 0.96 (0.65–1.40) 0.82 1.00 1.79 (1.25–2.55) 0.001 0.008 1.08 (0.79–1.47) 0.65 1.00
Allergic rhinitis
 Adjusted model 1 0.87 (0.72–1.04) 0.12 0.18 1.38 (1.14–1.68) 0.001 0.005 1.25 (1.05–1.50) 0.02 0.04 1.24(0.93–1.63) 0.14 0.19 2.01 (1.57–2.56) < 0.001 < 0.001 1.24 (1.01–1.52) 0.04 0.08
 Adjusted model 2 0.87 (0.72–1.04) 0.12 0.19 1.38 (1.13–1.68) 0.001 0.005 1.25 (1.04–1.50) 0.02 0.04 1.23 (0.93–1.63) 0.15 0.21 1.99 (1.56–2.55) < 0.001 < 0.001 1.23 (1.00–1.51) 0.05 0.10
 Adjusted model 3 0.86 (0.72–1.04) 0.11 0.19 1.36 (1.12–1.66) 0.002 0.01 1.24 (1.04–1.49) 0.02 0.05 1.22 (0.92–1.61) 0.18 0.25 1.95 (1.52–2.49) < 0.001 < 0.001 1.21 (0.99–1.49) 0.07 0.14
Eczema
 Adjusted model 1 1.25 (1.02–1.53) 0.04 0.05 1.78 (1.42–2.23) < 0.001 < 0.001 1.70 (1.39–2.08) < 0.001 < 0.001 1.39 (1.00–1.94) 0.05 0.06 1.69 (1.28–2.24) < 0.001 < 0.001 1.58 (1.27–1.96) < 0.001 < 0.001
 Adjusted model 2 1.26 (1.02–1.55) 0.03 0.04 1.77 (1.41–2.23) < 0.001 < 0.001 1.72 (1.40–2.10) < 0.001 < 0.001 1.40 (1.00–1.95) 0.05 0.06 1.69 (1.28–2.23) < 0.001 < 0.001 1.57 (1.26–1.94) < 0.001 < 0.001
 Adjusted model 3 1.26 (1.03–1.55) 0.03 0.04 1.76 (1.40–2.22) < 0.001 < 0.001 1.70 (1.39–2.08) < 0.001 < 0.001 1.39(0.99–1.93) 0.06 0.07 1.63 (1.23–2.16) 0.001 0.002 1.55 (1.24–1.92) < 0.001 < 0.001

Adjusted model 1 was adjusted for demographic characteristics, family structure and socioeconomic status

Adjusted model 2 was further adjusted for conditions of gestation, delivery and feeding besides the covariates in adjusted model 1

Adjusted model 3 was further adjusted for health problems, daily activity and behavior routine besides the covariates in adjusted model2

Subscale 1, difficulty in falling asleep; Subscale 2, difficulty in maintaining sleep; Subscale 3, difficulty in reinitializing sleep; Subscale 4, difficulty in returning to wakefulness; Subscale 5, sleep-disordered breathing; Subscale 6, disorders of arousal

*p value corrected

aStatistically significant results (p < 0.05) are in italics