Fig. 2.

Untreated patients with high tumor co-expression of progranulin and sortilin have worse breast cancer-specific survival. a Kaplan-Meier curves illustrating breast cancer-specific survival on combined progranulin and sortilin expression, making a double high group (high progranulin, high sortilin expression) against all other combinations (of low/high progranulin/sortilin expression) for the randomized untreated patients only (n=206). b BCSS looking at all different progranulin/sortilin combinations in randomized untreated group only (n=206). The statistical differences between the curves, as well as HR and 95% CI were estimated by the log-rank test. BCSS: breast cancer-specific survival, HR: hazard ratio, CI: confidence interval, PGRN: progranulin, SORT: sortilin