Table 2.
The associations of SBP trajectories with adverse maternal outcomes
| Maternal outcomes | Low-stable | Low delayed-increasing | Low reverse-increasing | Medium reverse-increasing | Medium-stable | High-stable |
|---|---|---|---|---|---|---|
| (n = 3893) | (n = 1521) | (n = 4454) | (n = 3352) | (n = 4404) | (n = 2729) | |
| Gestational hypertension (n, %) | 8 (0.53%) | 57 (1.28%) | 205 (6.12%) | 15 (0.39%) | 50 (1.14%) | 357 (13.08%) |
| Model 1 | 1.00 (reference) | 1.37 (0.58–3.23) | 3.35 (1.90–5.93) | 16.84 (9.95–28.51) | 2.97 (1.67–5.30) | 38.91 (23.15–65.39) |
| Model 2 | 1.00 (reference) | 1.42 (0.52–3.85) | 3.34 (1.72–6.48) | 17.25 (9.35–31.80) | 2.48 (1.25–4.93) | 36.56 (19.90–67.17) |
| Model 3 | 1.00 (reference) | 1.70 (0.63–4.63) | 1.15 (0.58–2.26) | 3.16 (1.66–6.02) | 1.07 (0.53–2.14) | 5.28 (2.76–10.10) |
| Preeclampsia/eclampsia (n, %) | 10 (0.66%) | 28 (0.63%) | 30 (0.89%) | 25 (0.64%) | 46 (1.04%) | 43 (1.58%) |
| Model 1 | 1.00 (reference) | 1.02 (0.49–2.14) | 0.98 (0.57–1.68) | 1.40 (0.82–2.38) | 1.63 (1.00–2.66) | 2.48 (1.51–4.07) |
| Model 2 | 1.00 (reference) | 1.37 (0.63–2.95) | 1.07 (0.59–1.96) | 1.52 (0.84–2.75) | 1.72 (0.99–3.00) | 2.17 (1.21–3.90) |
| Model 3 | 1.00 (reference) | 1.50 (0.69–3.24) | 0.81 (0.43–1.55) | 0.93 (0.47–1.87) | 1.36 (0.76–2.43) | 1.23 (0.60–2.53) |
Model 1 was unadjusted;
Model 2 was adjusted for maternal age at delivery (in years, continuous), early pregnancy BMI (Kg/m2, continuous), gestation, parity, presence of GDM;
Model 3 was additionally controlled for SBP (mmHg, continuous) at the first visit, and SBP measurement times (continuous) during pregnancy, based on model 2