Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Diagram of the stepwise evaluation of endpoints in the EMPEROR‐Reduced and EMPEROR‐Preserved trials. The figure shows planned alpha for each analysis. The final alpha is determined by an alpha‐spending function that depends on number of events at time of the interim analysis of each trial.
