FIGURE 1.

Magnetic resonance imaging sequence design. A, One of the lines of the Hadamard encoding matrix is applied (dark red, label; light red, control), followed by the T₂‐relaxation‐under‐spin‐tagging (TRUST) T₂‐preparation (T₂‐prep) module, then the bipolar gradient, and finally the image acquisition scheme. A‐H, The eight Hadamard images acquired following the corresponding line in the labeling scheme. B, The sequence interleaves the acquisition of different effective TEs (eTEs) and gradient strengths within the dynamic cycle. Abbreviations: BGS, background suppression pulse; PLD, postlabeling delay; V_enc, encoding velocity