Figure 3. Modelling of soleus muscle oxygen tension.

Simulation of muscle PO₂ at rest (A–B) and maximal rate of oxygen consumption (D–E) in representative images. There were no significant differences in simulations of muscle PO₂ at rest (Type I fibres: 27.26 ± 0.33 vs. 27.54 ± 0.30 mmHg, P = 0.099; Type IIa: 27.12 ± 0.39 vs. 27.37 ± 0.31 mmHg, P = 0.16; all fibres: 27.25 ± 0.33 vs. 27.52 ± 0.29 mmHg, P = 0.102) (C) or at maximal rate of oxygen consumption (Type I: 18.97 ± 1.38 vs. 20.11 ± 1.27 mmHg, P = 0.109; Type IIa: 18.00 ± 1.64 vs. 19.07 ± 1.36 mmHg, P = 0.177; all fibres: 18.92 ± 1.36 vs. 20.02 ± 1.24 mmHg, P = 0.115) (F). Areas of muscle hypoxia (PO₂ < 0.5 mmHg) are highlighted in blue. [Color figure can be viewed at wileyonlinelibrary.com]