Table 4.

QoL free text responses to question 3

How does SMA affect your social life?
	Age			Motor function
	Adolescents n = 44% (95% CI)	Young Adults n = 41% (95% CI)	p value	Non independent sitter n = 31% (95% CI)	Sitter/non-independent walker n = 40% (95% CI)	Independent walker n = 14% (95% CI)	p value
Accessibility	11.36 (3.79–24.56)	26.83 (14.22–42.94)	0.068	16.13 (5.45–33.73)	22.5 (10.84–38.45)	14.29 (1.78–42.81)	0.708
Activity limitation	18.18 (8.19–32.71)	14.63 (5.57–29.17)	0.659	12.9 (3.63–29.83)	15 (5.71–29.84)	28.57 (8.39–58.10)	0.423
Communication difficulties	4.55 (0.56–15.47)	9.76 (2.72–23.13)	0.349	12.9 (3.63–29.83)	5 (0.61–16.92)	0	0.312
Dating	2.27 (0.06–12.02)	2.44 (0.06–12.9)	1	0	5 (0.61–16.92)	0	0.653
Dependence	6.82 (1.43–18.66)	7.32 (1.54–19.9)	1	0	15 (5.71–29.84)	0	0.04*
Feeling judged	11.36 (3.79–24.56)	0	0.056	3.23 (0.08–16.70)	7.5 (1.57–20.39)	7.14 (0.18–33.9)	0.705
Misunderstood	6.82 (1.43–18.66)	12.2 (4.08–26.20)	0.474	19.35 (7.45–37.47)	2.5 (0.06–13.16)	7.14 (0.18–33.9)	0.056
No effect	27.27 (14.96–42.79)	9.76 (2.72–23.13)	0.053	19.35 (7.45–37.47)	15 (5.71–29.84)	28.57 (8.39–58.10)	0.533
No social life	9.09 (2.53–21.67)	4.88 (0.60–16.53)	0.677	12.9 (3.63–29.83)	2.5 (0.06–13.16)	7.14 (0.18–33.9)	0.209
Other	2.27 (0.06–12.02)	12.2 (4.08–26.20)	0.102	3.23 (0.08–16.70)	10 (2.79–23.66)	7.14 (0.18–33.9)	0.542

‘No effect’ on socialization was most commonly cited by non-independent sitter, though it was followed closely by major effects including accessibility concerns and an absence of socialization. Percentages are out of total number of respondents (n = 85). The table values represent statistically significant differences in responses between either the age groups (2 bins) or between the motor function groups (3 bins) using a chi square or Fisher’s exact test. Highlighted findings were found to have statistical significance; asterisk (*) indicates significance by Fisher’s exact test and carrots (^) indicates significance by Chi2 test