Table 3.

Polymer PFAS toxicity, physical, and chemical properties

	Polymer PFAS
Description	Side‐chain fluorinated polymers			Fluoropolymer	Perfluoropolyether
Substance	6:2 Fluorotelomer acrylatea	6:2 Fluorotelomer methacrylatea	1H,1H‐perfluorooctyl methacrylatea	Polytetrafluoroethylene (PTFE)	1,1,1,2,2,3,3‐heptafluoro‐3‐(1,1,2,2,2‐pentafluoroethoxy)propane
CAS number	17527‐29‐6	2144‐53‐8	3934‐23‐4	9002‐84‐0	60164‐51‐4
Structure
Chain length	Short	Short	Long	N/A	N/A
Molecular weight	418.15	432.18	468.16	389 000–45 000 000	NDA
Physical state/description	Colorless liquid	Yellow liquid	Liquid	Solid	Colorless, viscous liquid
Boiling point	210.2 °C	210 °C	70 °C	Not applicable	NDA
Melting point	Not applicable for liquids	Not applicable for liquids	Not applicable for liquids	326 °C	NDA
Vapor pressure	259 Pa at 25 °C	8.6 Pa at 25 °C	NDA	NDA	NDA
Stability (hydrolysis, photolysis, oxidation, thermal, biological)	Unstable	Unstable	NDA	Stable	Stable
Water solubility (USP 2011)	0.185 mg·L−1 at 25 °C	0.042 mg·L−1 at 20 °C	NDA	Practically insoluble or insoluble (1 × 10−5 mg·L−1)	Insoluble
Log K OW	NDA	5.2 at 23 °C	NDA	NDA	NDA
Particle size µm	Not applicable for liquids	Not applicable for liquids	Not applicable for liquids	100 to 500 µm (powders)	Not applicable for liquids
Acute dermal LD50	NDA	>5000 mg/kg	NDA	NDA	>17 000 mg/kg
Skin irritant, Y or N	N	N	Y	N	N
Eye irritant, Y or N	N	N	Y	N	N
Skin sensitizer, Y or N	N	N	NDA	N	N
90‐d animal feeding study (no effect dose)	NDA	5 mg/kg‐day	NDA	NDA	NDA
Mutagen, Y or N	N	N	NDA	N	N
Caused tumors in lab rats, Y or N	NDA	NDA	NDA	N	NDA
Half‐life in humans	NDA	NDA	NDA	N/A	NDA
References	(Sigma Aldrich 2018b; ECHA 2020a).	(Anand et al. 2012; ECHA 2019a, 2020b; Sigma Aldrich 2020)	(ECHA Substance Infocard 12/21/2019; Sigma Aldrich 2017)	(Henry et al. 2018)	(DuPont SDS 11/2014)

PFAS = per‐ and polyfluoroalkyl substances; PTFE = polytetrafluoroethylene; NDA = no data available.

^aNote these data are for the fluorinated side‐chains.