Figure 6.
Optimal VSV lag is stratified by intrinsic tumor growth rates. (A) Waterfall plot of the change in tumor size 15 days after the last VSV administration for the one enhancer protocol. Bar color depicts the optimal VSV lag. Corresponding tumor growth rate () for each patient are plotted in gray. (B) Waterfall plot of the change in tumor size 15 days after the last VSV administration for the seven enhancer protocol. Bar color depicts the optimal VSV lag. Corresponding tumor growth rate () for each patient are plotted in gray. (C) Ordering of protocols from best (bottom row) to worst (top row) for each patient based on the tumor size 15 days after the last VSV administration for seven enhancer protocol. Corresponding tumor growth rates are plotted above (patient ordering identical based on intrinsic tumor growth rate as in B. The ordering of the optimal VSV lag for the one enhancer protocol is provided in online supplemental figure S6 in online supplemental information). VSV: vesicular stomatitis virus.