TABLE 2.
Associated expression of mRNA with copy number alteration in conventional adenoma
| Official symbol | Location | Up‐regulated case (n = 15) (%) | Pattern of copy number alteration (n = 15) (%) | P‐value | |
|---|---|---|---|---|---|
| Gain | Non‐gain | ||||
| MIR3654 | 7q33 | 10 (66.7) | 4 (26.7) | 11 (73.3) | .5604 |
| OLFM4 | 13q14.3 | 7 (46.7) | 3 (20) | 12 (80) | .0769 |
| GNAS | 20q13.32 | 9 (60) | 2 (13.3) | 13 (86.7) | 1.000 |
| RPS21 | 20q13.33 | 8 (53.3) | 2 (13.3) | 13 (86.7) | 1.000 |
| RPL41 | 12q13.2 | 10 (66.7) | 1 (6.7) | 14 (93.3) | 1.000 |
| CEACAM5 | 19q13.2 | 9 (60) | 1 (6.7) | 14 (93.3) | 1.000 |
| PIGR | 1q32.1 | 11 (73.3) | 0 (0) | 15 (100) | 1.000 |
| TMSB10 | 2p11.2 | 8 (53.3) | 0 (0) | 15 (100) | 1.000 |
| SPTBN1 | 2p16.2 | 8 (53.3) | 0 (0) | 15 (100) | 1.000 |
| EPCAM | 2p21 | 8 (53.3) | 0 (0) | 15 (100) | 1.000 |
| ITM2C | 2q37.1 | 8 (53.3) | 0 (0) | 15 (100) | 1.000 |
| CAST | 5q15 | 12 (80) | 0 (0) | 15 (100) | 1.000 |
| SLC12A2 | 5q23.3 | 7 (46.7) | 0 (0) | 15 (100) | 1.000 |
| RACK1 | 5q35.3 | 8 (53.3) | 0 (0) | 15 (100) | 1.000 |
| SNORD95 | 5q35.3 | 8 (53.3) | 0 (0) | 15 (100) | 1.000 |
| SNORD96A | 5q35.3 | 8 (53.3) | 0 (0) | 15 (100) | 1.000 |
| H4C3 | 6p22.2 | 9 (60) | 0 (0) | 15 (100) | 1.000 |
| EEF1A1 | 6q13 | 11 (73.3) | 0 (0) | 15 (100) | 1.000 |
| EEF1G | 11q12.3 | 10 (66.7) | 0 (0) | 15 (100) | 1.000 |
| RPS3 | 11q13.4 | 10 (66.7) | 0 (0) | 15 (100) | 1.000 |
| SNORD15A | 11q13.4 | 10 (66.7) | 0 (0) | 15 (100) | 1.000 |
| HSPA8 | 11q24.1 | 13 (86.7) | 0 (0) | 15 (100) | 1.000 |
| SNORD14C | 11q24.1 | 13 (86.7) | 0 (0) | 15 (100) | 1.000 |
| SNORD14D | 11q24.1 | 13 (86.7) | 0 (0) | 15 (100) | 1.000 |
| RPS28 | 19p13.2 | 10 (66.7) | 0 (0) | 15 (100) | 1.000 |
| CSTB | 21q22.3 | 8 (53.3) | 0 (0) | 15 (100) | 1.000 |
| RPL3 | 22q13.1 | 12 (80) | 0 (0) | 15 (100) | 1.000 |
| SNORD43 | 22q13.1 | 12 (80) | 0 (0) | 15 (100) | 1.000 |
| SNORD83B | 22q13.1 | 12 (80) | 0 (0) | 15 (100) | 1.000 |
| MT‐CO1 | MT | 9 (60) | 0 (0) | 15 (100) | 1.000 |
| MT‐CO2 | MT | 8 (53.3) | 0 (0) | 15 (100) | 1.000 |
Abbreviations: CN‐LOH, copy neutral loss of heterozygosity; LOH, loss of heterozygosity.