TABLE 5.
Associated increased expression level of mRNA with copy number alteration in CRC
| Official symbol | Location | Up‐regulated case (n = 19) (%) | Pattern of copy number alteration (n = 19) (%) | P‐value | |
|---|---|---|---|---|---|
| Gain | Non‐gain | ||||
| DDX27 | 20q13.13 | 18 (94.7) | 18 (94.7) | 1 (5.3) | .0326 |
| MAPRE1 | 20q11.21 | 15 (79) | 17 (89.5) | 2 (10.5) | .0351 |
| ACSS2 | 20q11.22 | 15 (79) | 17 (89.5) | 2 (10.5) | .0351 |
| PHF20 | 20q11.22‐q11.23 | 16 (84.2) | 17 (89.5) | 2 (10.5) | .0175 |
| OSBPL2 | 20q13.33 | 15 (79) | 17 (89.5) | 2 (10.5) | .0351 |
| DHX35 | 20q11.23‐q12 | 10 (52.6) | 17 (89.5) | 2 (10.5) | 1.000 |
| SEMG1 | 20q13.12 | 9 (47.4) | 17 (89.5) | 2 (10.5) | .4737 |
| ZFP64 | 20q13.2 | 12 (63.2) | 17 (89.5) | 2 (10.5) | .1228 |
| CAB39L | 13q14.2 | 9 (47.4) | 16 (84.2) | 3 (15.8) | .2105 |
| DACH1 | 13q21.33 | 12 (63.2) | 16 (84.2) | 3 (15.8) | .5232 |
| TPX2 | 20q11.21 | 12 (63.2) | 16 (84.2) | 3 (15.8) | .5232 |
| DEFB126 | 20p13 | 12 (63.2) | 12 (63.2) | 7 (36.8) | .3261 |
| ODF1 | 8q22.3 | 11 (57.9) | 11 (57.9) | 8 (42.1) | .1809 |
| VIRMA | 8q22.1 | 11 (57.9) | 0 (0) | 19 (100) | 1.000 |
Abbreviations: CN‐LOH, Copy neutral loss of heterozygosity; LOH, loss of heterozygosity.