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. 2020 Apr 19;117(3):743–755. doi: 10.1093/cvr/cvaa069

Figure 3.

Figure 3

TFR cells increase BREG and FOB cell population. (A) Effect of Bcl-6 inhibitor on secondary lymphoid organs B cell populations on an NCD and HCD fed mice (PLN FOB: n = 6 mice/group; PLN MZB: n = 5–7 mice/group; PLN BREG: n = 3–5 mice/group; spleen FOB: n = 5–7 mice/group; spleen MZB: n = 5–8 mice/group; spleen BREG: n = 5–8 mice/group). (B) Effect of TFR cell transfer on secondary lymphoid organs B cell populations on NCD and HCD fed mice (PLN FOB: n = 5–8 mice/group; PLN MZB: n = 5–8 mice/group; PLN BREG: n = 5–7 mice/group; spleen FOB: n = 4–7 mice/group; spleen MZB: n = 4–8 mice/group; spleen BREG: n = 5–7 mice/group). The non-parametric Mann–Whitney U test was used for statistical analysis: *P ≤ 0.05; **P ≤ 0.005; ***P ≤ 0.0005. All data were represented as mean ± SEM.