Table 1.
Characteristics of Cases and Controls at the Pre-COVID-19 Assessment (Only Survivors)
| Cases (n = 56) | Controls (n = 74) | P Value | |
|---|---|---|---|
| Sex, female, n (%) | 41 (73.2) | 55 (74.3) | .82 |
| Age, y, mean ± SD | 84.4 ± 7.3 | 85.1 ± 7.4 | .75 |
| Educational level, primary school or less, n (%) | 28 (52.8) | 44 (62.8) | .26 |
| Number of drugs, median (IQR) | 7 (5, 10) | 8 (6, 11) | .43 |
| Chronic diseases (moderate severity according to CIRS), n (%) | |||
| Cardiac | 28 (50.0) | 30 (40.5) | .21 |
| Hypertension | 25 (44.6) | 35 (46.1) | .72 |
| Vascular/hematological | 26 (46.4) | 32 (43.2) | .56 |
| Respiratory | 13 (23.2) | 18 (24.3) | .82 |
| Ophthalmologic and otorhinolaryngologic | 20 (35.7) | 17 (23.0) | .08 |
| Upper gastrointestinal | 19 (33.9) | 46 (62.2) | .01 |
| Lower gastrointestinal | 18 (32.1) | 26 (35.1) | 1.00 |
| Hepatic and pancreatic | 4 (7.1) | 5 (6.8) | .71 |
| Renal | 4 (7.1) | 4 (5.4) | 1.00 |
| Genitourinary | 39 (69.6) | 58 (78.4) | .53 |
| Musculoskeletal and dermatologic | 32 (57.1) | 58 (78.4) | .04 |
| Neurologic (excluding dementia) | 21 (37.5) | 36 (48.7) | .09 |
| Endocrine - metabolic | 23 (41.1) | 31 (41.9) | .49 |
| Psychiatric/behavioral | 51 (91.1) | 68 (91.9) | .74 |
| CIRS-comorbidity index, median (IQR) | 5 (4, 6) | 5 (4, 6) | .27 |
| CIRS-severity index, median (IQR) | 2.1 (1.9, 2.3) | 2.2 (2, 2.4) | .12 |
| MMSE, mean ± SD | 16.3 ± 7.4 | 16.8 ± 7.8 | .42 |
| No. residents with available ratings | n = 48 | n = 61 | |
| Handgrip (kg), mean ± SD | 8.6 ± 4.2 | 8.6 ± 5.7 | .07 |
| No. residents with available ratings | n = 24 | n = 45 | |
| 4-m walking test (m/s), mean ± SD | 0.8 ± 0.2 | 0.5 ± 0.2 | .10 |
| No. residents with available ratings | n = 15 | n = 23 | |
| Frail-NH score (range 0–13) | 7.4 ± 3.4 | 7.8 ± 3.1 | .79 |
| Frailty (Frail-NH score >7), n (%) | 30 (53.6) | 50 (67.5) | .10 |
| Frailty, n (%) | .16 | ||
| Nonfrail (Frail-NH score 0–1) | 8 (14.3) | 7 (9.5) | |
| Mild or moderate frailty (Frail-NH score 2–5) | 12 (21.4) | 9 (12.2) | |
| Most frail (Frail-NH score 6–14) | 36 (64.3) | 58 (78.3) |
CIRS, cumulative illness rating scale; IQR, interquartile range; SD, standard deviation.