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. 2021 Feb 22;49(6):694–700. doi: 10.1016/j.ajic.2021.02.012

Table 3.

Association of influenza vaccine and positive COVID-19 test: multivariable analysis

Variable Comparator Odds Ratio (95% CI) P-value
Influenza vaccination Yes vs No 0.76 (0.68, 0.86) <.0001
Chronic Pulmonary Disease, Congestive Heart Failure, Diabetes or Hypertension Yes vs No 1.28 (1.06, 1.53) <0.001
Unknown vs No 0.22 (0.09, 0.56)
Ethnicity Non-Hispanic/Latino vs Hispanic/Latino 1.55 (1.02, 2.33) 0.02
Unknown vs Hispanic/Latino 2.01 (1.21, 3.32)
Age 35-49 vs <35 1.54 (1.28, 1.84) <0.001
50-64 vs <35 1.48 (1.24, 1.76)
≥65 vs <35 1.25 (1.03, 1.50)
Unknown vs <35 0.63 (0.31, 1.27)
BMI 18.5-24.9 vs <18.5 1.95 (1.14, 3.32) <0.001
25-29.9 vs <18.5 3.11 (1.85, 5.24)
30-39.9 vs <18.5 3.50 (2.09, 5.87)
>40 vs <18.5 4.26 (2.48, 7.31)
Unknown vs <18.5 5.92 (3.56, 9.82)
Elixhauser Score Per Unit Increase 1.15 (1.12, 1.18) <.001
Gender Female vs Male 0.85 (0.76, 0.96) .01
Race Caucasian vs African American 0.23 (0.20, 0.27) <.001
Other vs African American 0.56 (0.44, 0.70)
Unknown vs African American 0.46 (0.32, 0.67)
Smoking Status Former Smoker vs Current Smoker 1.88 (1.32, 2.69) <.001
Tobacco User vs Current Smoker 0.79 (0.19, 3.38)
Never Smoker vs Current Smoker 2.52 (1.79, 3.53)
Unknown vs Current Smoker 3.02 (2.15, 4.24)