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. Author manuscript; available in PMC: 2021 Oct 1.
Published in final edited form as: Pain. 2020 Oct;161(10):2410–2424. doi: 10.1097/j.pain.0000000000001973

Table 3.

Summary table of mRNA expression for each target in mouse vs human DRG. These data summarize all data shown in the pie charts of all figures. ND = not detected

% total neuronal population % nociceptors (CGRP and/or P2X3R positive) % other neurons (CGRP and/or P2X3R-negative) Total # neurons assessed
Target Mouse Human Mouse Human Mouse Human Mouse Human
CD68 non-neuronal non-neuronal non-neuronal non-neuronal non-neuronal non-neuronal
CALCA 32.9 59.1 32.9 59.1 0 0 12714 5388
CHRNA6 30.3 43.8 27.7 34.4 2.6 9.40 1194 410
CHRNA9 ND 25.6 ND 25.3 ND 0.30 468
CHRNA10 1.65 3.68 1.32 3.01 0.33 0.67 1682 366
CRLF2 70.4 4.57 52.1 3.83 18.3 0.74 1348 360
HCN1 70.9 94.4 43.4 73.9 27.5 20.5 1483 334
HCN2 71.5 44.0 44.2 24.9 27.3 19.1 1266 331
HDAC6 86.6 58.0 60.2 48.1 26.4 9.90 1344 326
KCNB1 85.4 65.2 20.2 605
KCNS1 55.5 42.4 29.4 12.1 26.1 30.3 1176 368
P2RX3 66.3 52.6 66.3 52.6 0 0 12714 5388
SCN9A 96.0 69.0 27.0 285
SCN10A 71.0 71.0 0 529
TRPA1 55.2 16.3 53.6 16.0 1.60 0.30 1606 583
TRPV1 32.4 74.7 29.8 66.6 2.54 8.10 1438 423