Table 2.
Clinical Characteristics of Patients With CCO Compared With Patients Without CCO Who Underwent Either CAS or CEA
| CAS Cohort | CEA Cohort | |||||
|---|---|---|---|---|---|---|
| CCO Status | CCO Status | |||||
| CCO (n = 3,185) | No CCO (n = 28,500) | p Value | CCO (n = 1,439) | No CCO (n = 25,299) | p Value | |
| Age, yrs | 69.1 ± 9.6 | 71.0 ± 9.8 | <0.01 | 70.4 ± 9.9 | 71.0 ± 9.9 | 0.02 |
| Male | 2,160 (67.8) | 17,469 (61.3) | <0.01 | 955 (66.4) | 14,806 (58.5) | <0.01 |
| Caucasian | 2,942 (92.4) | 26,399 (92.6) | 0.60 | 1,351 (93.9) | 23,795 (94.1) | 0.79 |
| Hispanic or Latino ethnicity | 119 (3.7) | 1,258 (4.4) | 0.08 | 51 (3.6) | 961 (3.8) | 0.62 |
| Previous carotid revascularization | 958 (30.1) | 8,483 (29.8) | 0.71 | 207 (14.4) | 3,873 (15.3) | 0.34 |
| ESRD on dialysis | 86 (2.7) | 653 (2.3) | 0.15 | 19 (1.3) | 406 (1.6) | 0.40 |
| Diabetes mellitus | 1,274 (40.0) | 11,206 (39.4) | 0.461 | 508 (35.4) | 9,143 (36.2) | 0.53 |
| Left main coronary artery stenosis ≥50% | 187 (5.9) | 1,608 (5.6) | 0.60 | 89 (6.3) | 1,027 (4.1) | <0.01 |
| Multivessel coronary artery stenoses ≥70% | 906 (28.4) | 8,235 (28.9) | 0.60 | 384 (26.9) | 5,559 (22.2) | <0.01 |
| Prior heart failure | 559 (17.6) | 4,850 (17.0) | 0.44 | 181 (12.6) | 2,634 (10.4) | <0.01 |
| Smoker | 2,530 (79.4) | 21,020 (73.8) | <0.01 | 1,097 (76.2) | 18,113 (71.6) | <0.01 |
| Prior TIA | 1,006(31.6) | 9,146 (32.1) | 0.56 | 368 (25.6) | 6,043 (23.9) | 0.14 |
| Prior ischemic stroke | 725 (22.8) | 4,695 (16.5) | <0.01 | 290 (20.2) | 3,736 (14.8) | <0.01 |
| NYHA functional class III/IV | 174 (5.5) | 1,705 (6.0) | 0.24 | 41 (2.8) | 479 (1.9) | 0.01 |
| Target lesion symptoms | 1,505 (47.3) | 12,469 (43.8) | <0.01 | 593 (41.2) | 9,143 (36.1) | <0.01 |
| CAS restenosis | 152 (4.8) | 709 (2.5) | <0.01 | 6 (0.4) | 39 (0.2) | 0.03 |
| CEA restenosis Urgent | 462 (14.5) | 3,557 (12.5) | <0.01 | 28(1.9) 43 | 303 (1.2) 600 | 0.01 |
| cardiac surgery | 91 (2.9) | 590 (2.1) | <0.01 | (3.0) | (2.4) | 0.14 |
| Peripheral arterial disease | 1,426 (44.8) | 11,425(40.1) | <0.01 | 487 (33.8) | 7,524 (29.8) | <0.01 |
| Laryngeal nerve palsy | 0.54 | |||||
| No | 3,152 (99.1) | 28,197 (99.1) | 1,430 (99.4) | 25,105 (99.4) | 1.0 | |
| Yes, right | 28 (0.9) | 249 (0.9) | 9 (0.6) | 158 (0.6) | ||
| Yes, bilateral | 1 (0.0) | 4 (0.0) | 0 (0.0) | 1 (0.0) | ||
| Neck surgery (other than CEA) | 224 (7.0) | 1,646 (5.8) | <0.01 | 50 (3.5) | 447 (1.8) | <0.01 |
| Tracheostomy present | 42 (1.3) | 264 (0.9) | 0.03 | 2 (0.1) | 41 (0.2) | 1.00 |
| Previous neck radiation | 236 (7.4) | 1,765 (6.2) | <0.01 | 19 (1.3) | 210 (0.8) | 0.05 |
| Ischemic heart disease | 1,623 (51.0) | 15,093 (53.0) | 0.04 | 640 (44.5) | 10,405 (41.1) | 0.01 |
| Ml within 6 weeks | 85 (2.7) | 603 (2.1) | 0.04 | 26 (1.8) 85 | 330 (1.3) | 0.12 |
| LVEF <40% | 329 (10.3) | 2,781 (9.8) | 0.30 | (5.9) | 1,210 (4.8) | 0.05 |
| Thrombus present | 110 (3.5) | 1,037 (3.7) | 0.60 | 84 (5.8) | 1,525 (6.0) | 0.78 |
Values are mean SD or n (%).
ESRD = end-stage renal disease; LVEF = left ventricular ejection fraction; MI = myocardial infarction; NYHA = New York Heart Association; TIA = transient ischemic attack; other abbreviations as in Table 1.