Table 3.
Area Under the ROC Curve (AUC), Sensitivity, and Specificity of Different Markers of Inflammation, Coagulation, and Sepsis Measured Upon Hospital Admission (T1)
| WBC | NLR | hsCRP | Fibrinogen | D-dimer | IL-6 | TNF-α | Ferritin | PCT | 25(OH)D | |
|---|---|---|---|---|---|---|---|---|---|---|
| Sensitivity (%) | 55 | 61 | 83 | 41 | 74 | 90 | 60 | 57 | 65 | 59 |
| Specificity (%) | 71 | 78 | 59 | 82 | 61 | 42 | 60 | 79 | 65 | 70 |
| Cutoff | >8.2 | >8.3 | >53.7 | >741 | >1015 | >14.6 | >18.6 | >1103 | >0.2 | <8.7 |
| AUC; 95% CI | 0.614; 0.527 to 0.696 | 0.718; 0.634 to 0.791 |
0.719; 0.635 to 0.794 |
0.634; 0.542 to 0.719 |
0.708; 0.621 to 0.786 |
0.665; 0.575 to 0.746 |
0.570; 0.472 to 0.663 |
0.709; 0.594 to 0.808 |
0.647; 0.544 to 0.740 |
0.617; 0.53 to 0.699 |
ROC = receiver operating characteristic, CI = confidence interval, WBC = white blood cell, NLR = neutrophil-to-lymphocyte count ratio, hsCRP = high-sensitivity C-reactive protein, IL-6 = interleukin 6, TNF-α = tumor necrosis factor alpha, PCT = procalcitonin, 25(OH)D = 25-hydroxyvitamin D.