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Cumulative incidence plot showing the association of the presence of (A) aortic valve calcification and (B) mitral calcification on the composite endpoint of cardiovascular death (CVD), non-fatal myocardial infarction (NFMI), or non-fatal stroke (NFS). The adverse outcomes associated with valve calcification were no longer evident once the burden of coronary atherosclerosis was considered in the multivariable model.
