Table 1.
Parameter | Included patients (n = 366) | Patients lost to follow-up (n = 107) | Odds ratio (95% CI) or mean difference ± SD | p value |
Patient gendera | 0.51b | |||
Female | 45 (164) | 41(44) | ||
Male | 55 (202) | 59 (63) | 1.16 (0.74 to 1.8) | |
Patient age (years)c | 59.0 (43.0 to 70.0) | 63.0 (50.0 to 76.0) | 0.003d | |
Patient BMI (kg/m2)e | 28.9 ± 7.0 | 28.9 ± 6.9 | -0.02 ± 6.95 | 0.98f |
Largest tumor dimension (cm)c | 7.0 (4.0 to 11.2) | 7.5 (4.5 to 15.0) | 0.32d | |
Categorical tumor sizea | 0.71d | |||
≤ 5 cm | 37 (137) | 41 (44) | ||
> 5, ≤ 10 cm | 32 (118) | 30 (32) | 0.91 (0.54 to 1.54) | |
> 10 cm | 30 (111) | 29 (31) | 0.94 (0.55 to 1.61) | |
Tumor locationa | 0.15b | |||
Lower extremity | 56 (206) | 67 (72) | ||
Upper extremity | 18 (67) | 18 (19) | 0.79 (0.44 to 1.42) | |
Back/torso/neck | 10 (37) | 3 (4) | 0.33 (0.11 to 0.95) | |
Pelvis/sacrum | 9 (32) | 6 (6) | 0.55 (0.22 to 1.38) | |
Acral (hand/foot) | 7 (24) | 6 (6) | 0.74 (0.29 to 1.87) | |
Tumor deptha | 0.63b | |||
Superficial | 14 (50) | 11 (12) | ||
Deep | 86 (316) | 89 (94) | 1.21 (0.62 to 2.4) | |
Tumor gradea | 0.13d | |||
Low | 12 (43) | 17 (18) | ||
Intermediate | 2 (7) | 3 (3) | 0.98 (0.23 to 4.21) | |
High | 86 (315) | 80 (86) | 0.61 (0.33 to 1.11) | |
Tumor marginsa | 0.020d | |||
Positive margins | 29 (104) | 22 (23) | ||
< 0.1 cm | 21 (76) | 18 (19) | 1.15 (0.58 to 2.25) | |
< 0.5 cm | 20 (72) | 18 (19) | 1.07 (0.53 to 2.14) | |
≥ 0.5 cm | 30 (111) | 42 (45) | 1.87 (1.06 to 3.31) | |
Operative closurea | 0.30b | |||
Primary | 95 (346) | 93 (99) | ||
Flap | 5 (20) | 7 (8) | 1.41 (0.60 to 3.3) |
Data are presented as: aN (%), cmedian (IQR), or emean 6 SD; p values were calculated using the following: +Fisher's Exact test, dKruskal-Wallis test, fANOVA. p < 0.05 indicates significance.