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. Author manuscript; available in PMC: 2022 Jan 1.
Published in final edited form as: Paediatr Drugs. 2020 Nov 24;23(1):55–73. doi: 10.1007/s40272-020-00428-w

Table 3.

Incidence of seizures in antidepressant and anti-anxiolytic drugs [43].

Category Incidence of Seizures
N # of seizures %
Antidepressant drugs
Group 1
Buproprion IR 4419 26 6.0
Group 2
Citalopram 4168 12 0.3
Fluoxetine 6000 12 0.2
Venlafaxine 2181 3 0.1
Bupropion SR 3094 3 0.1
Paroxetine 2963 2 0.07
Nefazodone 2256 1 0.04
Mirtazapine 2796 1 0.04
Escitalopram 715 0 0
Duloxetine 2314 0 0
Sertraline 2979 0 0
Anti-anxiety drugs
Group 1
Alprazolam (1983 trial) 1723 46 2.7
Group 2
Alprazolam (1990 trial) 1698 7 0.4
Buspirone 3558 3 0.8