Figure 1.

A heatmap summarizing predicted susceptibility to SARS-CoV-2 for species with confirmed infection from in vivo experimental studies or from documented natural infections. Studies that make predictions about species susceptibility are shown on the x-axis, organized by method of prediction (those relying on ACE2 sequences, estimating binding strength using three dimensional structures, or laboratory experiments). Predictions about zoonotic capacity from this study are listed in the second to last column, with high and low categories determined by zoonotic capacity observed in Felis catus. Confirmed infections for species along the y-axis are summarized in⁵⁹ and are depicted as a series of filled or unfilled circles. Bolded species have been experimentally confirmed to transmit SARS-CoV-2 to naive conspecifics. Species predictions range from warmer colors (yellow: low susceptibility or zoonotic capacity for SARS-CoV-2) to cooler colors (purple: high susceptibility or zoonotic capacity). See Supplementary Methods (https://doi.org/10.25390/caryinstitute.c.5293339) for detailed methods about study categorization.