Table 1.
Chemical, analytical, and physical data of derivatives EMAC10157 a-b-d-g and EMAC10160 a-b-d-g.
| Compound | R | C, %; H, % |
M.P., °C | Yield, %a | Aspect | |
|---|---|---|---|---|---|---|
| Calc. | Found | |||||
| EMAC10157a | 4-CH3 | C, 71.07; H, 6.20 | C, 71.10; H, 6.19 | 132–133 | 80 | White crystals |
| EMAC10157b | 4-OCH3 | C, 68.48; H, 5.98 | C, 68.74; H, 5.97 | 127–130 | 89 | Pale brown crystals |
| EMAC10157d | 4-F | C, 67.60; H, 5.44 | C, 67.79; H, 5.45 | 164–166 | 90 | White crystals |
| EMAC10157g | 4-C6H5 | C, 74.36; H, 5.82 | C, 74.55; H, 5.45 | 138–140 | 71 | White crystals |
| EMAC10160a | 4-CH3 | C, 74.24; H, 5.98 | C, 74.19; H, 5.99 | 226–229 | 98 | Grey crystals |
| EMAC10160b | 4-OCH3 | C, 71.41; H, 5.75 | C, 71.68, H, 5.76 | 202–205 | 97 | Green crystals |
| EMAC10160d | 4-F | C, 70.58; H, 5.18 | C, 70.30; H, 5.16 | 135–139 | 92 | Grey crystal |
| EMAC10160g | 4-C6H5 | C, 77.24; H, 5.62 | C, 77.52; H, 5.60 | 248–250 | 97 | Pale brown crystal |
a
Yields are referred to the last step of the synthetic pathway.