Skip to main content
. 2020 Aug 5;17(2):503–509. doi: 10.1080/21645515.2020.1776034

Table 2.

Vaccine effectiveness of 2 RV1 doses vs 0 doses, by age group and rotavirus-case severity status

  Cases No. (%)
with 2 doses
No. (%)
with 0 doses
Controls No. (%)
with 2 doses
No. (%)
with 0 doses
VE of 2 doses vs 0 doses1 95% CI
All cases: age ≥6 months1 92 76 (83) 16 (17) 452 400 (88) 52 (12) 51 2–75
Age 6 through 11 months 37 30 (81) 7 (19) 259 227 (88) 32 (12) 52 −40–84
Age ≥12 months2 55 46 (84) 8 (16) 193 173 (90) 20 (10) 60 −9–85
Higher severity cases3: age ≥6 months                
Cases with IVF 84 68 (81) 16 (19) 452 400 (88) 52 (12) 55 10–78
Cases hospitalized for ≥5 days 62 50 (81) 12 (19) 452 400 (88) 52 (12) 57 2–81
Cases with score ≥9 46 38 (83) 8 (17) 452 400 (88) 52 (12) 52 −19–81
Cases with score ≥10 28 23 (82) 5 (18) 452 400 (88) 52 (12) 60 −19–86
Cases with score ≥11 23 18 (78) 5 (22) 452 400 (88) 52 (12) 67 0–89

IVF, intravenous fluids.1Models included rotavirus vaccine status (2 doses, 1 dose or 0 doses), birth month, birth year, admission quarter, admission year.

2Oldest case was aged 31 months, and oldest control was aged 30 months.

3Severity score calculated based on Supplemental Table 1. The scored categories included the top 58%, 35% and 29% of the cases, respectively. The models for scored categories controlled for the birth quarter instead of birth month, to reduce degrees of freedom given lower case counts.