Figure 3.

SEC-UV-MALS profiles of (a) stressed antibody (45°C 10 days, 45C10d), (b) the receptor HER2, and (c) the stressed antibody-receptor mixture with a binding ratio of 1:1. The UV absorbance is shown in solid lines. The y-axis on the left represents the milli Absorbance Units of UV at 280 nm. The MALS data are displayed as dots, and the y-axis of the determined molecular weight is shown on the right. Cartoons of antibody, receptor, and antibody-receptor complexes are shown on top of each assigned peak based on the experimentally measured molecular weight