Table 3.
Overall incidence per 100,000 person-years of otitis media/acute otitis media in the pre-PCV, PCV7, and PHiD-CV/PCV13 cohorts*
| Cohort | ≤2 years | 3–5 years | ≤5 years |
|---|---|---|---|
| Skåne Incidence rate (95% CI) | |||
| pre-PCV | 40,843 (40,574; 41,113) |
22,034 (21,871; 22,199) |
29,721 (29,574; 29,868) |
| PCV7 | 31,469 (30,996; 31,949) |
17,623 (17,061; 18,203) |
27,583 (27,208; 27,964) |
| PHiD-CV | 23,697 (23,367; 24,032) |
17,994 (15,325; 21,128) |
23,640 (23,312; 23,973) |
| VGR Incidence rate (95% CI) | |||
| pre-PCV | 34,501 (34,287; 34,717) |
20,819 (20,682; 20,958) |
26,376 (26,257; 26,497) |
| PCV7 | 33,099 (32,559; 33,648) |
17,848 (17,269; 18,445) |
28,275 (27,861; 28,694) |
| PCV13 | 25,710 (25,433; 25,990) |
15,270 (14,283; 16,325) |
25,268 (24,999; 25,539) |
CI = confidence interval, PCV = pneumococcal conjugate vaccine, PCV7/PCV13 = 7-valent/13-valent pneumococcal conjugate vaccine, PHiD-CV = pneumococcal non-typeable Haemophilus influenzae protein D conjugate vaccine, VGR = Västra Götalandsregionen
*the PCV7 era was short in VGR and Skåne and any change detected vs the PCV7 cohort in the incidence of otitis media/acute otitis media should be considered with caution