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. 2021 Feb 15;2021:6647258. doi: 10.1155/2021/6647258

Figure 5.

Figure 5

Sepsis-induced neuroinflammation was attenuated by Senkyunolide I treatment. (a) TNF-α, (b) IL-1β, and (c) IL-6 in the hippocampus homogenate were measured at 24 h after CLP surgery. (d) Representative bands showed the levels of p-JNK, JNK, p-ERK, ERK, p-P38, P38, p-P65, and P65 protein in hippocampus tissue at 24 h after surgery. The relative quantification of p-JNK/JNK (e), p-ERK/ERK (f), p-P38/P38 (g), and p-P65/P65 (h) was analyzed. Values were the mean ± SEM (n = 6 for each group). ∗∗P < 0.01 vs. sham groups; ##P < 0.01 vs. CLP+DMSO group; #P < 0.05 vs. CLP+DMSO group. SEI: Senkyunolide I; CLP: cecal ligation and puncture.