FIGURE 2.

Effect of Azan-7 on agr-regulated gene transcription. (A) Graphic representation showing the category of microarray results in MRSA after 16 h of culture with Azan-7 (100 μM). All the major virulence factors are represented; the others are representative of the category. (B) qPCR was performed to assess mRNA transcript levels of hla, psmα, cap1A, agrA, hysA, and cap1C in MRSA treated with Azan-7 (100 μM) or DMSO 0.05% for 16 h. Results are reported as log₂ of relative gene expression. The data are expressed as mean ± SEM, n = 3. ***P < 0.001; **P < 0.01; *P < 0.05 vs. MRSA treated with DMSO 0.05%.