Table 3.
Baseline and post-surgery changes in CD patients with remission or no remission at follow-up.
| Remission (n=65) | Non-Remission (n=6) | pa | pb | pc | |||
|---|---|---|---|---|---|---|---|
| Baseline | Post-surgery | Baseline | Post-surgery | ||||
| Surgical complications(n/%) | – | 17(26.2%) | – | 0(0.0%) | – | – | 0.324 |
| GHD | – | 9(13.8%) | – | 0(0.0%) | – | – | 1.000 |
| HH | – | 8(12.3%) | – | 0(0.0%) | – | – | 1.000 |
| DI | – | 1(5.9%) | – | 0(0.0%) | – | – | 1.000 |
| Follow-up(months) | – | 16.83(12.7–23.40) | – | 15.11(8.09–17.88) | – | – | 0.217 |
| F[8am](μg/dl) | 27.21(20.55–33.95) | 8.90(5.30–11.55) | 21.75(16.43–29.04) | 30.3(28.4–33.19) | <0.001* | 0.063 | <0.001* |
| ACTH(pg/ml) | 61.70(45.25–97.00) | 16.70(9.30–25.15) | 52.25(39.35–56.80) | 43.55(26.58–61.08) | <0.001* | 0.438 | <0.001* |
| 24hUFC(μg) | 433.30(285.28–609.35) | 29.55(16.70–41.98) | 298.11(196.95–483.20) | 280.15(162.15–649.49) | <0.001* | 1.000 | <0.001* |
| TC(mmol/L) | 5.70 ± 1.27 | 4.83 ± 1.12 | 5.63 ± 0.79 | 5.68 ± 1.15 | <0.001* | 0.844 | 0.121 |
| TG(mmol/L) | 1.42(0.96–1.88) | 1.16(0.86–1.85) | 1.05(0.93–1.42) | 1.09(0.90–1.27) | 0.153 | 1.000 | 0.678 |
| HDL-c(mmol/L) | 1.42(1.20–1.71) | 1.14(0.99–1.35) | 1.33(1.11–1.40) | 1.54(1.13–1.62) | <0.001* | 0.438 | 0.023* |
| LDL-c(mmol/L) | 3.37(2.71–4.11) | 2.92(2.32–3.45) | 3.65(3.24–4.26) | 3.93(2.94–4.55) | <0.001* | 1.000 | 0.276 |
| Total/HDL-c Ratio | 3.95(3.17–4.80) | 4.03(3.31–5.03) | 4.34(3.92–5.40) | 4.00(3.34–4.64) | 0.339 | 0.125 | 0.253 |
| Hyperlipidemia(n/%) | 22(33.8%) | 13(20.0%) | 1(16.7%) | 3(50.0%) | 0.049* | 0.625 | 0.012* |
| Hypercholesterolemia(n/%) | 21(32.3%) | 7(10.8%) | 1(16.7%) | 3(50.0%) | 0.001* | 0.625 | 0.004* |
| Hypertriglyceridemia(n/%) | 8(12.3%) | 9(13.8%) | 0(0.0%) | 0(0.0%) | 1.000 | 1.000 | 1.000 |
| HbA1c(%) | 5.50(5.20–5.90) | 5.30(4.93–5.50) | 5.50(5.25–5.80) | 5.40(5.33–5.55) | 0.001* | 0.625 | 0.935 |
GHD, growth hormone deficiency; HH, Hypogonadotropic hypogonadism; DI, diabetes insipidus; F[8am], serum cortisol (8am); ACTH, adrenocorticotropic hormone; TC, total cholesterol; TG, triglycerides; HDL-c, high-density lipoprotein cholesterol; LDL-c, low-density lipoprotein cholesterol. *Statistically significant. pa, p value for comparing baseline and post-surgery characteristics in remission group. pb, p value for comparing baseline and post-surgery characteristics in non-remission group. pc, p value for comparing the change rates of each parameters before and after surgery between remission and non-remission group.