Table 4.
Comparison of baseline and post-surgery characteristics of CD patients with biochemical remission after surgery presenting with improved or persisted hyperlipidemia status at last follow-up.
| Change in hyperlipidemia status | |||
|---|---|---|---|
| Improved | Persisted | p | |
| Patient(n/%) | 13(51.9%) | 9(48.1%) | – |
| Follow-up(months) | 19.55(16.89–26.85) | 19.10(14.54–20.00) | 1.000 |
| Age(years) | 32.54 ± 15.92 | 36.56 ± 11.78 | 0.246 |
| Gender(Female)(n/%) | 12(92.3%) | 8(88.9%) | 0.784 |
| BMI(kg/m2) | 27.39(24.72–29.31) | 26.39(23.39–28.55) | 0.647 |
| Disease duration (months) | 34.00(7.00–102.50) | 24.00(9.00–36.00) | 0.471 |
| SBP(mmHg) | 139.46 ± 19.51 | 146.56 ± 12.30 | 0.645 |
| DBP(mmHg) | 91.38 ± 16.16 | 93.56 ± 12.05 | 0.766 |
| HT(n/%) | 7(53.8%) | 8(88.9%) | 0.165 |
| TC(mmol/L) | 6.70 ± 0.68 | 7.53 ± 1.04 | 0.033* |
| TG(mmol/L) | 1.79(1.38–2.52) | 2.19(1.40–3.16) | 0.431 |
| HDL(mmol/L) | 1.44(1.24–1.73) | 1.68(1.39–2.12) | 0.393 |
| LDL(mmol/L) | 4.14(3.82–4.83) | 4.42(4.09–5.17) | 0.262 |
| Total/HDL-c Ratio | 4.98(3.66–5.09) | 4.67(3.44–5.32) | 0.948 |
| FBG(mmol/L) | 4.80(4.20–5.90) | 4.90(4.65–5.85) | 0.556 |
| 2h-BG(mmol/L) | 10.20(8.45–11.25) | 10.60(9.35–12.20) | 0.431 |
| HbA1c(%) | 5.65(4.90–5.95) | 5.80(5.35–6.15) | 0.382 |
| IGM(n/%) | 12(92.3%) | 9(100.0%) | 1.000 |
| F[8am](μg/dl) | 30.85(25.78–36.15) | 21.30(19.18–32.60) | 0.110 |
| ACTH(pg/ml) | 70.20(53.00–101.80) | 56.20(54.20–78.10) | 0.357 |
| 24hUFC(μg) | 496.60(331.25–708.02) | 357.28(202.30–443.73) | 0.239 |
| Tumor size(mm) | 5.40(5.00–7.75) | 5.50(3.95–8.45) | 0.905 |
| Visceral obesity(n/%) | 12(92.3%) | 6(66.7%) | 0.264 |
| HRT(n/%) | 4(30.8%) | 1(11.1%) | 0.360 |
| HRT Duration(months) | 9.64(4.69–30.3) | 30.28 | 0.800 |
| Post-surgery GHD(n/%) | 3(23.1%) | 0(0.0%) | 0.240 |
| Post-surgery HH(n/%) | 1(7.7%) | 1(11.1%) | 1.000 |
BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; HT, hypertension; TC, total cholesterol; TG, triglycerides; HDL-c, high-density lipoprotein cholesterol; LDL-c, low-density lipoprotein cholesterol; FBG, fasting blood glucose; 2h-BG, 2h-blood glucose during OGTT; IGM, impaired glucose metabolism; F[8am], serum cortisol (8am); ACTH, adrenocorticotropic hormone; 24hUFC, 24-h urine free cortisol; HRT, hydrocortisone replacement therapy. GHD, growth hormone deficiency; HH, Hypogonadotropic hypogonadism. *Statistically significant.