TABLE 2.

Comparison of clinical variables, microbiota composition, and histology between the no dysbiosis group (n = 10) and the dysbiosis group (n = 11) after successful H. pylori eradication.

	No dysbiosis	Dysbiosis	p-Value
	n = 10	n = 11
Male, n (%)	4 (40.0)	4 (36.4)	0.864
Age, years	58.3 ± 10.4	62.0 ± 10.4	0.092
Current smoker (n = 20), n (%)	0 (0.0)	1 (10.0)	1.000
Drinker, n (%)	2 (20.0)	2 (18.2)	1.000
AG or IM*	9 (90.0)	4 (36.4)	0.011
Relative abundance of Acinetobacter genus at baseline	1.3 ± 2.1	29.8 ± 26.5	0.005
Histology at baseline (updated Sydney classification)
H. pylori
Antrum	1.5 ± 1.1	1.5 ± 0.7	0.909
Corpus	1.8 ± 0.8	1.8 ± 1.0	0.963
Neutrophil infiltration
Antrum	1.5 ± 1.1	2.1 ± 0.3	0.125
Corpus	2.2 ± 0.4	1.6 ± 0.8	0.034
Monocyte infiltration
Antrum	1.8 ± 0.4	1.9 ± 0.3	0.500
Corpus	2.2 ± 0.4	1.9 ± 0.5	0.188
AG
Antrum	1.3 ± 0.7	0.6 ± 0.8	0.102
Corpus	0.9 ± 0.8	0.4 ± 0.7	0.273
IM
Antrum	1.0 ± 0.8	0.4 ± 0.7	0.113
Corpus	0.6 ± 0.8	0.1 ± 0.3	0.098
PG I/II ratio	2.0 ± 0.7	5.6 ± 4.3	0.022

p-Values were calculated using the chi-square test or Student’s t-test. *Histological grade ≥ 1 atrophic gastritis or intestinal metaplasia and pepsinogen I/II ratio < 2.5. “Dysbiosis” means Acinetobacter predominance after H. pylori eradication. Bold style indicates statistical significance. AG, atrophic gastritis; IM, intestinal metaplasia; PG, pepsinogen