Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Feb 22;11:4317. doi: 10.1038/s41598-021-83700-4

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Methylene blue staining. (a,a′) Bone resorption lacuna of the NIs formed by some osteoclasts (black arrows) inside the thread in the 2nd week. (b,b′) Bone resorption lacuna of the CIs formed on the surface by some osteoclasts (black arrows) inside the thread in the 2nd week. (c,c′) On the 4th week, some bone resorption lacunae were formed on the surface of the NIs. (d,d′) In the 4th week, the bone resorption area of the control group increased, and deep pink new bone (NB) was observed. (e,e′) In the 8th week, almost no osteoclasts were observed, and extensive NB was observed between the threads. (f,f′) Almost no osteoclasts were observed in the experimental group, and the boundary between new and old bone became blurred. (g,g′) The boundary between new and old bone became more blurred for the NIs. (h,h′) Mineralized bone was observed on the surface of the CIs, and the NB became more mature in the 12th week. OS (osteoclasts); NB (new bone); OB (old bone); (MB) mineralized bone. Scale bars represent 50 μm (a–h) and 100 μm (a′–h′); original magnification: (a–h) × 10, (a′–h′) × 20.