Table 2.
Univariable and multivariable linear regression analyses for identification of variables associating with serum free thiol levels in the study population.
| Variable | Univariable analysis | Multivariable analysis | ||
|---|---|---|---|---|
| St. Beta | P-value | St. Beta | P-value | |
| Age (years) | −0.297 | <0.001 | −0.132 | <0.001 |
| BMI (kg/m2) | −0.198 | <0.001 | ||
| Waist circumference (cm) | −0.208 | <0.001 | −0.090 | <0.001 |
| Current smoking (%) | 0.077 | <0.001 | 0.066 | 0.001 |
| Alcohol use (%) | 0.087 | <0.001 | ||
| Systolic blood pressure (mmHg) | −0.196 | <0.001 | ||
| Diastolic blood pressure (mmHg) | −0.079 | <0.001 | ||
| CVD history (%) | −0.062 | 0.001 | ||
| Hypertension (%) | −0.183 | <0.001 | ||
| Diabetes (%) | −0.046 | 0.012 | ||
| Laboratory parameters | ||||
| Hemoglobin (mmol/L) | −0.003 | 0.873 | ||
| hs-CRP (mg/L) | −0.136 | <0.001 | −0.095 | <0.001 |
| Albumin (g/L) | 0.050 | 0.007 | ||
| Creatinine (μmol/L) | −0.151 | <0.001 | ||
| eGFR (mL/min/1.73 m2) | 0.321 | <0.001 | 0.219 | <0.001 |
| AST (U/L) | −0.081 | <0.001 | ||
| ALT (U/L) | −0.030 | 0.105 | ||
| Total cholesterol (mmol/L) | −0.106 | <0.001 | ||
| LDL-cholesterol (mmol/L) | −0.168 | 0.017 | ||
| HDL–cholesterol (mg/dL) | 0.040 | 0.030 | ||
| Triglycerides (mg/dL) | −0.057 | 0.002 | 0.089 | <0.001 |
| Glucose (mmol/L) | −0.096 | <0.001 | ||
| Gynecological variables | ||||
| Pregnancy in past (%) | −0.018 | 0.337 | ||
| No. of children (%) | −0.129 | <0.001 | ||
| Hysterectomy (%) | 0.017 | 0.356 | ||
| Oophorectomy (%) | −0.002 | 0.932 | ||
| Current OCC use (%) | 0.005 | 0.782 | ||
| Current female hormone use (%) | 0.020 | 0.288 | ||
BMI, body mass index; CVD, cardiovascular disease; hs-CRP, high-sensitive C-reactive protein; eGFR, estimated glomerular filtration rate; AST, aspartate aminotransferase; ALT, alanine aminotransferase; LDL, low-density lipoprotein; HDL, high-density lipoprotein; OCC, oral contraceptives.