Figure 2.

Immune cell amino acid metabolism following mycobacterial infection. (A) L-ARG metabolism pathway in immune cells. (B) L-TRP metabolism pathway in immune cells. (C) Amino acid metabolism between myeloid and T cells. Abbreviations: L-ARG, L-arginine; L-CIT, L-citrulline; L-ORN, L-ornithine; iNOS, inducible nitric oxide synthase; Ass1, argininosuccinate synthase 1; Asl, argininosuccinate lyase; Arg1/2, arginase 1/2; L-TRP, L-tryptophan; KYN, L-kynurenine; IDO, indolamine 2,3-dioxygenase; CAT1, cationic amino acid transport 1; CAT 2, cationic amino acid transporter 2; LAT1. L-type amino acid transporter 1.