Figure 6.
Small interfering RNA knockdown of respective TGFβs cause differential alterations of myofibroblast and collagen target expression
(A) Small interfering RNA (siRNA) knockdown of TGFβ mRNAs at 48 h post transfection with respective TGFβ siRNA construct.
(B) Effect of TGFβ siRNA knockdown on myofibroblast and ECM target transcription at 48 h post transfection in VICs.
Represented data are the average of three experiments ±SEM. Statistical comparisons employed one-way or two-way ANOVA followed by Dunnett's test. ∗p ≤ 0.05; ∗∗p ≤ 0.01; ∗∗∗p ≤ 0.005; ∗∗∗∗p ≤ 0.0001.