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. 2021 Feb 1;44(1):12–15. doi: 10.18773/austprescr.2020.064

Table 2. Efficacy of antidepressants compared to placebo.

Antidepressant Odds ratio 95% confidence interval
Amitriptyline 2.13 1.89–2.41
Mirtazapine 1.89 1.64–2.20
Duloxetine 1.85 1.66–2.07
Venlafaxine 1.78 1.61–1.96
Paroxetine 1.75 1.61–1.90
Fluvoxamine 1.69 1.41–2.02
Escitalopram 1.68 1.50–1.87
Sertraline 1.67 1.49–1.87
Vortioxetine 1.66 1.45–1.92
Agomelatine 1.65 1.44–1.88
Fluoxetine 1.52 1.40–1.66
Citalopram 1.52 1.33–1.74
Clomipramine 1.49 1.21–1.85
Desvenlafaxine 1.49 1.24–1.79
Reboxetine 1.37 1.16–1.63