Table 4. Symptoms and initial antidepressant choice.

Symptoms	Preferred antidepressant
Anxiety	Selective serotonin reuptake inhibitors Moclobemide
Weight loss, reduced appetite	Mirtazapine Mianserin
Sleep disturbance, insomnia	Agomelatine Mirtazapine Mianserin Tricyclic antidepressants
Sexual dysfunction	Agomelatine
Blunting, anhedonia, demotivation	Selective serotonin reuptake inhibitors Serotonin noradrenaline reuptake inhibitors Agomelatine Monoamine oxidase inhibitors Reboxetine
Melancholia, severe depression	Serotonin noradrenaline reuptake inhibitors Tricyclic antidepressants Vortioxetine Monoamine oxidase inhibitors
Pain	Duloxetine Tricyclic antidepressants
Cognitive difficulties	Vortioxetine