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. 2021 Feb 2;34(2):400–418. doi: 10.1007/s13577-020-00481-0

Fig. 12.

Fig. 12

Transmission electron microscopy images of the BRIN-BD (rat islets) cell culture model during conditions of hypoxia (O2 5%). Cell structure remained normal until approximately 10 min after the hypoxia. However, mitochondrial swelling and nuclear structure collapse findings became apparent around 15 min after the hypoxia (hypoxic condition period: a 0 min, b 5 min, c 10 min, d 15 min, e 30 min, and f 60 min)