Table 6.
Adrenal cortex cell (Y-1) culture under hypoxia
| Cultured time under hypoxia (min) |
Adrenal cortex cell culture (Y-1) | ||
|---|---|---|---|
| Corticosterone (ng/mL) (median) |
HIF1α (ng/mL) (median) |
VEGF (ng/mL) (median) |
|
| 0 | – | – | – |
| 5 | – | – | – |
| 10 | 7.1–7.9 (7.4) | 2.2–3.1 (2.6) | 10.8–12.8 (12.3) |
| 15 | – | – | – |
| 30 | 21.5–24.6 (22.8) | 31.6–34.4 (32.6) | 18.5–22.7 (20.6) |
| 60 | 51.6–54.8 (52.6) | 50.6–54.4 (52.8) | 45.2–49.5 (48.3) |
| 120 | 79.7–88.6 (82.6) | 39.4–43.6 (41.8) | 74.2–79.6 (76.2) |
| 240 | 60.7–66.7 (64.3) | 11.8–14.3 (12.8) | 96.7–105.2 (98.5) |
| 480 | 33.5–38.4 (35.5) | 6.8–8.1 (7.2) | 74.6–78.7 (77.1) |
| 720 | 19.7–22.4 (21.3) | 3.9–4.6 (4.2) | 44.2–48 (46.4) |
| 1440 | 10.3–12.6 (11.2) | 3.2–3.6 (3.5) | 33.7–36.3 (34.4) |
| 2880 | 5.1–7.1 (6.6) | 3.0–3.2 (3.2) | 17.8–21.2 (19.4) |
| 4320 | 4.1–5.0 (4.3) | 1.2–1.5 (1.3) | 12.3–14.1 (13.5) |