Table 1.

Clinical manifestations of dengue, Zika, and chikungunya

	Dengue	Zika	Chikungunya
Incubation period	5–8 days	3–14 days	1–12 days
Frequency of symptoms	~10% of infected patients.	~20% of infected patients.	~85% of infected patients.
Skin manifestations	- Facial, neck, and trunk flushing. - Morbilliform rash. - Hemorrhagic manifestations: petechiae and ecchymoses.	- Maculopapular rash involving, trunk, face, palms and soles. - Highly pruritic.	- Maculopapular rash involving trunk and limbs. - May be pruritic. - Centro facial hyperpigmentation of the skin (Chik sign)
Other important manifestations of disease	- High fevers (up to 40 °C). - Retro-orbital pain. - Nausea and vomiting.	- Non-purulent conjunctivitis. - Guillain-Barré Syndrome. - Microcephaly in neonates.	- High fevers (39–40 °C). - Severe polyarthralgia.