Table 1.
Correlation between exosomal miR-128-3p expression and clinicopathologic parameters of 66 patients with colorectal cancer.
| Parameters | n (%) | Exosomal miR-128-3p expression | ||
|---|---|---|---|---|
| Low | High | P | ||
| Gender | 0.641 | |||
| Male | 37 (56.1) | 20 | 17 | |
| Female | 29 (43.9) | 14 | 15 | |
| Age, years | 0.266 | |||
| <60 | 23 (34.8) | 14 | 9 | |
| ≥60 | 43 (65.2) | 20 | 23 | |
| Tumor site | 0.143 | |||
| Colon | 31 (47) | 13 | 18 | |
| Rectal | 35 (53) | 21 | 14 | |
| Tumor size, cm | 0.316 | |||
| <5 | 31 (47) | 18 | 13 | |
| ≥5 | 35 (53) | 16 | 19 | |
| Tumor grade | 0.397 | |||
| Poor | 8 (12.1) | 3 | 5 | |
| Moderate/Well | 58 (87.9) | 31 | 27 | |
| PNI | <0.001 | |||
| Absence | 42 (63.6) | 29 | 13 | |
| Presence | 24 (36.4) | 5 | 19 | |
| LVI | <0.001 | |||
| Absence | 43 (65.2) | 29 | 14 | |
| Presence | 23 (34.8) | 5 | 18 | |
| Tumor stage* | <0.001 | |||
| I~II | 35 (53) | 27 | 8 | |
| III~IV | 31 (47) | 7 | 24 | |
| CEA, ng/mL | 0.141 | |||
| <5 | 43 (65.2) | 25 | 18 | |
| ≥5 | 23 (34.8) | 9 | 14 | |
| CA 19–9, U/mL | 0.002 | |||
| <37 | 18 (27.3) | 15 | 3 | |
| ≥37 | 48 (72.7) | 19 | 29 | |
| Overall | 66 (100) | 34 | 32 | |
*
The 8th edition of the AJCC Cancer Staging Manual; Boldface indicates P < 0.05. PNI, perineural invasion; LVI, lymphovascular invasion; CEA, carcinoembryonic antigen; CA19–9, carbohydrate antigen 19–9.