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. 2021 Feb 9;12:627260. doi: 10.3389/fphys.2021.627260

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Copyright © 2021 Wray and Arrowsmith.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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SARS-CoV-2 and COVID19. (A) Representation of SARS-CoV-2 virus. (B) A molecular model showing the virus with spike proteins (red) and ACE2 (angiotensin converting enzyme 2) receptor (blue) on host cell surface. From Juan Gaertner/Science Photo Library, accessed 8/11/2020. (C) Covid19 entry via airways. (D) scheme showing TMPRSS activation of virus, followed by its internalization, processing and replication, Adapted from Ward P. et al. (2020). Available at: https://www.fpm.org.uk/blog/covid-19-sars-cov-2-pandemic. Accessed 8/11/2020.