Table 3.

Variables related to the severity of symptoms

Variable	Mild (n = 42) N (%)	Moderate/severe (n = 20) N (%)	OR [95% CI]	p value*
Education
<Primary school	11 (26.2)	2 (10)	0.84 [0.50–1.36]	0.486
Primary school	9 (21.4)	12 (60)
High school	7 (16.7)	4 (20)
>High school	15 (35.7)	2 (10)
Residence
Home-dwelling	40 (69)	18 (31)	2.22 [0.29–17.45]	0.588
Nursing home	2 (50)	2 (50)
Hypertension (yes)	19 (45.2)	12 (60)	1.72 [0.52–5.65]	0.371
Hypercholesterolemia (yes)	15 (38.1)	10 (50)	2.29 [0.65–7.91]	0.224
Diabetes (yes)	5 (11.9)	5 (25)	3.31 [0.67–16.33]	0.141
Obstructive sleep apnea (yes)	6 (14.3)	4 (20)	1.21 [0.23–6.41]	0.826
Smoking (yes)	14 (33.3)	13 (65)	2.97 [0.79–11.17]	0.106
Alcohol (yes)	18 (42.9)	12 (60)	1.52 [0.37–6.15]	0.561
APOE4 allele (yes)	14 (33.3)	6 (31.6)	0.73 [0.20–2.67]	0.632

	Mean (SD) [N]	Mean (SD) [N]	OR [CI 95%]	p value**
Systolic BP, mm Hg	142.8 (21.9) [42]	148.00 (20.38) [20]	1.07 [1.02–1.13]	0.005
Diastolic BP, mm Hg	77.2 (11) [42]	79.45 (13.05) [20]	1.04 [0.99–1.10]	0.091
Smoking severity***	6,665 (6,237) [14]	11,070 (13,341) [13]	0.95 [0.91–0.99]	0.015
Alcohol intake, g/week	75.5 (53.8) [22]	93 (56.8) [11]	1.08 [0.99–1.18]	0.082
Coffee intake, cups/week	4.2 (4.7) [36]	2 (2.9) [17]	0.37 [0.24–0.55]	<0.0001
Tea intake, cups/week	1.8 (3.1) [36]	0.6 (1.4) [17]	0.44 [0.20–0.86]	0.024

OR, odds ratio; CI, confidence interval; BP, blood pressure.

^*Logistic regression (mild as reference category); covariates: age and sex.

^**Linear regression with Poisson distribution (mild as reference category); covariates: age and sex.

^***Estimated total number of consumed packs of cigarettes as packs/day × years of active smoking × 365 days.