Table 1.
Immunological features of case 1
| Laboratory test | Value | Reference range |
|---|---|---|
| Immunoglobulins, mg/dL | ||
| IgG | 1,301 | 610–1,616 |
| IgM | 90 | 35–242 |
| IgA | 259 | 84–499 |
| IgG subclasses, mg/dL | ||
| IgG1 | 662 | 382–929 |
| IgG2 | 490 | 242–700 |
| IgG3 | 40 | 22–176 |
| IgG4 | 36 | 5–125 |
| Protective antibody titers (≥1.3 mg/mL) | ||
| against Streptococcus pneumoniae | ||
| post Pneumovax-23 administration | 13/23 | 12–22/23 |
| Diptheria Ab IgG, IU/mL | 1.3 | >0.1 protective |
| Tetanus Ab IgG, IU/mL | 2.9 | >0.1 protective |
| Lymphocyte subsets, /mm3 | ||
| Lymphocyte% | 28 | 14–44 |
| Absolute lymphocytes | 8,300 | 4,000–10,500 |
| CD3+CD4+% | 51 | 24–64 |
| CD3+CD4+ number | 1,185 | 477–1,634 |
| CD3+CD8+% | 33 | 12–45 |
| CD3+CD8+ number | 767 | 168–1,315 |
| CD4+/CD8+ ratio | 1.54 | 0.8–5.0 |
| CD3% | 84 | 58–89 |
| CD3+ number | 1,952 | 700–2,377 |
| CD19+ B% | 9 | 6–29 |
| CD19+ B number | 209 | 104–795 |
| CD56+ NK% | 5 | 2–32 |
| CD56+ NK number | 116 | 43–680 |
| NK function (LU30) | 11 | 7–125 |
| Mannose-binding lectin, ng/mL | 263 | ≥100 |
| Complement CH50 | 110 | 60–144 |
| Isohemagglutinin titers | ||
| Anti-B IgM titer | 1:16 | >1:32 |
| Anti-B IgG titer | 1:16 | >1:32 |