Table 2.
Immunological features of case 2 (CVID)
| Laboratory test | Value | Reference range |
|---|---|---|
| Immunoglobulins, mg/dL | ||
| IgG | 599a | 610–1,616 |
| IgM | 159 | 35–242 |
| IgA | 73a | 84–499 |
| IgG subclasses, mg/dL | ||
| IgG1 | 373a | 382–929 |
| IgG2 | 152a | 242–700 |
| IgG3 | 14a | 22–176 |
| IgG4 | 11 | 5–125 |
| Protective antibody titers (≥1.3 mg/mL) | ||
| against Streptococcus pneumoniae post | ||
| Pneumovax-23 administration | 7a/23 | 12–22/23 |
| Lymphocyte subsets, /mm3 | ||
| Lymphocyte% | 20 | 14–44 |
| Absolute lymphocytes | 1,780 | 900–3,300 |
| CD3+CD4+% | 78a | 31–61 |
| CD3+CD4+ number | 1,388a | 338–1,194 |
| CD3+CD8+% | 17 | 10–38 |
| CD3+CD8+ number | 303 | 85–729 |
| CD4+/CD8+ ratio | 4.58a | 0.9–3.7 |
| CD3% | 94a | 62–84 |
| CD3+ number | 1,673 | 619–1,847 |
| CD19+ B% | 3a | 5–26 |
| CD19+ B number | 53 | 51–473 |
| CD56+ NK% | 3 | 1–17 |
| CD3–CD16+CD56+ NK number | 53 | 12–349 |
| Isohemagglutinin titers | ||
| Anti-B IgM titer | 1:8 | >1:32 |
| Anti-B IgG titer | 1:8 | >1:32 |
CVID, common variable immunodeficiency disease.
a
Abnormal results.