Table 3.
CD4+ | TN | TCM | TEM | TEMRA | CD25highCD127– FoxP3+ (CD4 Treg) |
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---|---|---|---|---|---|---|---|---|---|---|---|
a Subpopulations of CD4+ T cells | |||||||||||
Patient #1 Patient #2 |
48.30 57.70 |
51.60 25.80 |
28.50 64.20 |
18.20 9.76 |
1.76 0.16 |
3.25 2.12 |
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CD8+ | TN | TCM | TEM | TEMRA | CCR7+CD45RA– CXCR3+ (CD8 Treg) |
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b Subpopulations of CD8+ T cells | |||||||||||
Patient #1 Patient #2 |
26.40 24.00 |
48.70 18.60 |
5.39 15.80 |
26.40 25.00 |
19.50 40.50 |
0.04 0.10 |
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CD4+ | cTFH | TFH1 | TFH2 | TFH17 | TFH1/TFH17 | CCR5+ CD25highFoxP3+ (TFR) |
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c Subpopulation of TFH cells | |||||||||||
Patient #1 Patient #2 |
44.40 56.00 |
10.70 8.59 |
29.00 28.8 |
39.40 22.70 |
25.90 38.50 |
5.66 10.10 |
1.50 0.70 |
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CD19+ | Naive | Transition | MZ | IgM mem CSM | GC | Plasmablast | CD21+ CD21Low B Reg | ||||
d Subpopulations of B cells | |||||||||||
Patient #1 Patient #2 |
4.30 4.18 |
84.20 65.20 |
5.67 16.80 |
7.61 15.00 |
6.19 13.10 |
5.66 15.10 |
0.00 0.01 |
0.31 0.26 |
95.40 1.30 90.10 5.10 |
8.22 16.40 |
TFH, follicular helper T; TN, T naïve; TEM, T effector memory; TCM, T central memory; TEMRA, T effector memory RA; TFH, follicular helper T; GC, germinal center; MZ, marginal zone; CSM, class-switch memory.