Table 1.
The basic characteristics and comorbidities of patients with COVID-19
| Studies | Disease severity | Patients, n | Age, n (%) |
Sex (male) n (%) | Obesitya n (%) |
Comorbidity n (%) |
Hypertension n (%) |
Diabetes n (%) |
CVD n (%) |
Ref. | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| >50 yr | >60 yr | >65 yr | ||||||||||
| Guan, Weijie | Severe | 173 | – | – | 44/163 (27.0) | 100 (57.8) | 67 (38.7) | 41 (23.7) | 28 (16.2) | 10 (5.8) | [1] | |
| Non-severe | 926 | 109/848 (12.9) | 540 (58.3) | 194 (21.0) | 124 (13.4) | 53 (5.7) | 17 (1.8) | |||||
| Huang, Chaolin | Severe | 13 | – | – | – | 11 (84.6) | 5 (38%) | 2 (15%) | 1 (8%) | 3 (23%) | [7] | |
| Non-severe | 28 | 19 (67.9) | 8 (29%) | 4 (14%) | 7 (25%) | 3 (11%) | ||||||
| Zhang, Jinjin | Severe Non-severe |
58 82 |
48 (82.8) 50 (61.0) |
– | – | 33 (56.9) 38 (46.3) |
46 (79.3) 44 (53.7) |
22 (37.9) 20 (24.4) |
8 (13.8) 9 (11.0) |
4 (6.9) 3 (3.7) |
[8] | |
| Xu, Yuhuan | Severe | 13 | 5 (38.5) | – | – | 7 (53.8) | – | – | – | – | [9] | |
| Non-severe | 37 | 10 (27.0) | 22 (59.5) | |||||||||
| Li, Kunhua | Severe | 25 | – | – | – | 15 (60) | 11 (44.0) | 2 (8.0) | 7 (28.0) | 1 (4.0) | [10] | |
| Non-severe | 58 | 29 (50) | 4 (6.9) | 3 (5.2) | 0 (0.0) | 0 (0.0) | ||||||
| Wan, Suxin | Severe | 40 | – | – | – | 21 (52.5) | 28 (70) | 4 (10) | 9 (22.5) | 6 (15) | [11] | |
| Non-severe | 95 | 52 (54.7) | 15 (16.3) | 9 (9.4) | 3 (3.1) | 1 (1) | ||||||
| Cai, Qingxian | Severe | 58 | 50 (86.21) | – | – | 39 (67.24) | – | 22 (37.9) | 8 (13.79) | 13 (22.41) | [12] | |
| Non-severe | 240 | 88 (36.67) | 106 (44.17) | 25 (10.4) | 12 (5.0) | |||||||
| Zhang, Gemin | Severe | 32 | – | 7 (21.9) | – | 21 (65.6) | – | – | – | – | [13] | |
| Non-severe | 63 | 10 (15.9) | 32 (50.8) | |||||||||
| Zheng, F. | Severe | 30 | – | – | – | 14 (46.7) | – | 12 (40) | 2 (6.7) | 2 (6.7) | [14] | |
| Non-severe | 131 | 66 (50.4) | 10 (7.6) | 5 (3.8) | 2 (1.5) | |||||||
| Cheng, Kebing | Severe | 181 | – | – | 42 (23.2) | 99 (54.7) | – | 53 (29.28) | 20 (11.05) | 16 (8.84) | [15] | |
| Non-severe | 282 | 36 (12.77) | 145 (51.42) | 54 (19.15) | 20 (7.09) | 12 (4.26) | ||||||
| Xiao, Kaihu | Severe | 36 | – | – | – | 20 (55.6) | 17 (47.2) | 5 (13.9) | 5 (13.9) | 2 (5.6) | [16] | |
| Non-severe | 107 | 52 (48.6) | 29 (27.1) | 12 (11.2) | 5 (4.7) | 3 (2.8) | ||||||
| Yuan, Jing | Severe | 31 | – | – | – | 18 (58.1) | 14 (45.2) | 4 (12.9) | 8 (25.8) | 0 (0) 1 (0.5) | [17] | |
| Non-severe | 192 | 88 (45.8) | 40 (20.8) | 21 (10.9) | 10 (5.2) | |||||||
| He, Xingwei | Severe | 54 | – | – | – | 34 (63.0) | – | 24 (44.4) | 13 (24.1) | 5 (9.3) | [18] | |
| Deng, Qing | Severe | 67 | – | – | – | 38 (56.7) | 28 (41.8) | – | 24 (35.8) | 14 (20.9) | 11 (16.4) | [19] |
| Non-severe | 45 | 19 (42.2) | 13 (28.9) | 12 (26.7) | 5 (11.1) | 4 (8.9) | ||||||
| Yao, Qingchun | Severe | 25 | – | – | 9/25 (36.0) | 13 (52.0) | 13 (52.0) | 9 (36.0) | 3 (12.0) | 2 (8.0) | [20] | |
| Non-severe | 83 | 8/83 (9.6) | 30 (36.1) | 12 (14.5) | 7 (8.4) | 2 (2.4) | 2 (2.4) | |||||
| Xu, Jing | Severe | 30 | – | – | – | 20 (66.7) | 12 (40.0) | [21] | ||||
| Non-severe | 125 | 67 (53.6) | 16 (12.8) | |||||||||
| Asghar, M.S. | ICU | 33 | – | – | – | [22] | ||||||
| Ward | 67 | |||||||||||
| Cao, Zhenhuan | Severe Non-severe |
27 53 |
– | – | – | 16 (59.3) 22 (41.5) |
4 (14.8) 16 (30.2) |
3 (11.1) 3 (5.7) |
5 (18.5) 5 (9.4) |
[23] | ||
| Pellaud, Charlotte | ICU | 49 | – | 34 (70.0) | – | 30 (61.0) | 28 (19) | 40 (82.0) | 27 (55) | 11 (22) | 6 (12) | [24] |
| Ward | 147 | 114 (77.0) | 89 (60.0) | 13 (27) | 122 (83.0) | 91 (62) | 41 (28) | 20 (14) | ||||
| Chen, Qingqing | Severe | 43 | – | 34 (70.0) | – | 23 (53.5) | 9 (20.9) | 7 (16.3) | [25] | |||
| Non-severe | 102 | 114 (77.0) | 56 (54.9) | 13 (12.7) | 7 (6.9) | |||||||
| Liu, Changquan | Severe | 42 | 28 (66.7) | 41 (97.6) | [26] | |||||||
| Non-severe | 236 | 102 (43.2) | 197 (83.5) | |||||||||
| Ebinger, Joseph E. | ICU | 77 | 57 (74.0) | 17 (22.1) | 49 (63.6) | 26 (33.8) | 18 (23.4) | [27] | ||||
| Ward | 137 | 78 (56.9) | 27 (19.7) | 68 (49.6) | 40 (29.2) | 27 (19.7) | ||||||
| Hong, Kyung Soo | ICU Not-ICU |
13 85 |
6 (46.2) 23 (27.1) |
6 (46.2) 32 (37.6) |
5 (38.5) 33 (38.8) |
5 (38.5) 25 (29.4) |
3 (23.1) 6 (7.1) |
0 (0) 11 (12.9) |
[28] | |||
| Huang, Rui | Severe | 23 | 5 (21.7) | 17 (73.9) | 8 (44.4) | 9 (39.1) | 2 (8.7) | 8 (34.8) | 1 (4.3) | [29] | ||
| Non-severe | 179 | 21 (11.7) | 99 (55.3) | 16 (10.4) | 46 (25.7) | 27 (15.1) | 11 (6.1) | 6 (3.3) | ||||
| Liu, Fang | Severe | 33 | 8 (24.2) | 22 (66.7) | 12 (36.4) | 13 (39.4) | [30] | |||||
| Non-severe | 107 | 41 (38.3) | 41 (38.3) | 22 (20.6) | 22 (20.6) | |||||||
| Shahriarirad, Reza | ICU | 11 | 3 (27.3) | 7 (63.6) | 5 (45.5) | 3 (27.3) | 4 (36.4) | [31] | ||||
| Not-ICU | 102 | 25 (24.5) | 64 (62.7) | 17 (16.7) | 13 (12.7) | 12 (11.8) | ||||||
| Geehan, Suleyman | ICU | 141 | 92 (65.3) | 80 (56.7) | 37 (26.2) | 111 (78.7) | 73 (51.8) | 26 (18.4) | [32] | |||
| Not-ICU | 214 | 110 (51.4) | 85 (39.7) | 38 (17.8) | 147 (68.7) | 83 (38.8) | 30 (14.0) | |||||
| Zheng, Yufen | Severe | 29 | 16 (55.2) | 11 (37.9) | [33] | |||||||
| Non-severe | 112 | 58 (51.7) | 58 (51.8) | |||||||||
| Almazeedi, Sulaiman | ICU | 42 | 32 (76.2) | 17 (40.5) | 18 (42.9) | 8 (19.0) | [34] | |||||
| Not-ICU | 1,054 | 856 (81.2) | 160 (15.2) | 137 (13.0) | 33 (3.1) | |||||||
| Cao, Min | ICU | 19 | 15 (78.9) | 17 (89.5) | 6 (31.6) | 2 (10.5) | 5 (26.3) | [35] | ||||
| Not-ICU | 179 | 54 (30.1) | 84 (46.9) | 36 (20.1) | 13 (7.3) | 7 (3.9) | ||||||
COVID-19, coronavirus disease 2019; ICU, intensive care unit.
a
Obesity: BMI >30 or 28 kg/m2 (China).