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. 2021 Feb 9;8:586833. doi: 10.3389/fbioe.2020.586833

TABLE 2.

Comparison between HPH and PEF treatment for release of SpA.

Log reduction Product release Impurity load
DNA load
ET load
(logN/N0) (%) (%) Reduction (%) (mg/g SpA) Reduction (%) (EU/g SpA) Reduction (%)
HPH −3a 100 69 ± 2 112.2 ± 8.7 8.2 ± 0.2 × 109
PEF −0.27 85 ± 1 41 ± 3 40 ± 4 4.7 ± 0.1 96 ± 0 4.7 ± 0.08 × 109 43 ± 2

aAssuming -1 log per passage at 1,000 bar (Wuytack et al., 2002).